Gabapentin

Originally used for nerve pain and seizures, gabapentin can reduce hot flashes—especially overnight.

“It didn’t fix everything, but I finally slept through the night. That alone changed my life.”

How to Get It

Prescription only. Often used off-label for menopause.

Treatment Timeline

1–2 weeks for sleep; 2–4 weeks for hot flash reduction

Insurance Details

$10–$30/month with insurance; ~$40–$70 without

More about

Gabapentin

What to Love

This is a great option if your flashes wake you up more than they bother you during the day. Side effects like dizziness and drowsiness are common, but some women find them helpful for sleep.

How it Works

Usually taken at night, 300mg to start. Doses may be increased gradually. Do not stop suddenly.

Gabapentin affects nerve activity and has shown benefit in reducing hot flashes, especially in women who experience sleep disruption.

Gabapentin isn’t hormonal, but it helps regulate thermoregulation and pain sensitivity in the brain. It’s particularly effective for women who suffer night sweats and have trouble sleeping as a result.