A brand-new, non-hormonal drug that cools hot flashes by targeting the brain—not your hormones.
“For the first time in years, I went a full day without a single hot flash. I almost cried.”
$200–$550/month without insurance; many insurers now covering
Prescription required. Still rolling out to many pharmacies. May need prior authorization.
✅ Increasingly more covered, but it does vary across providers
1–3 weeks for relief
More about
Fezolinetant (Veozah)
This is a groundbreaking option for women who can’t or don’t want hormone therapy. It’s well-tolerated for most but can affect liver enzymes, so monitoring is required. It’s more expensive than older medications but shows real promise.
Veozah is the first FDA-approved non-hormonal treatment that directly targets hot flashes via the brain’s thermoregulation center.
Veozah blocks neurokinin B, a chemical that spikes as estrogen drops and confuses the brain’s internal thermostat. It doesn’t alter hormones—it simply dials down the brain’s overreaction to heat signals.
Avoid if you have liver disease or take strong CYP1A2 inhibitors (like fluvoxamine)
Headache, diarrhea, liver enzyme elevation
One 45mg pill daily, with or without food. Liver function tests needed before and during use.
Veozah (only one available)
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