A tiny tablet you insert into your vagina a few times per week to relieve dryness and irritation.
“It’s tiny and simple—I pop it in like a tampon and go to bed. No mess, no fuss.”
$30–$60/month with insurance; ~$90–$130 without
Available at most retail pharmacies. Generic options available.
Usually covered
1–2 weeks for noticeable change; full effects in 6–8 weeks
More about
Vaginal Tablet (Suppository)
Suppositories are discreet, convenient, and low-risk. They’re especially helpful for those who want to avoid creams or find applicators awkward. You’ll need to be consistent at first, but many women love the ease once they get the routine down.
This low-dose estradiol is placed directly into the vagina to treat local symptoms without significantly affecting systemic hormone levels.
These tablets dissolve slowly and restore estrogen to the vaginal walls and urinary tissues. They’re often recommended for women who want a less messy alternative to cream and are effective in maintaining vaginal tissue health with minimal systemic absorption.
Generally safe. Avoid if you have unexplained vaginal bleeding or haven’t ruled out hormone-sensitive cancers.
Insert using the provided applicator (or finger). Most use daily for 2 weeks, then switch to 2–3 times weekly.
Vagifem, Yuvafem, Imvexxy
FLUXX © 2025